{"id":6706,"date":"2025-04-03T05:44:09","date_gmt":"2025-04-03T05:44:09","guid":{"rendered":"https:\/\/app-66b73b11c1ac1859509cd621.closte.com\/?p=6706"},"modified":"2025-08-07T11:42:53","modified_gmt":"2025-08-07T11:42:53","slug":"human-metabolism-and-the-calorie-conundrum-2","status":"publish","type":"post","link":"https:\/\/www.fitnessnetwork.com.au\/personal-training\/human-metabolism-and-the-calorie-conundrum-2\/","title":{"rendered":"Human metabolism and the calorie conundrum"},"content":{"rendered":"\n<p><strong>Energy in minus energy out\u2019 is not as simple as it may seem, with a host of factors affecting both parts of the equation, writes dietitian and sports nutritionist&nbsp;<em>Brian St. Pierre<\/em>.<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>THE QUICK READ<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The Energy Balance Equation of \u2018Energy in \u2013 Energy out\u2019 is commonly used for calculating weight loss, or gain, over time<\/li>\n\n\n\n<li>People\u2019s frustrations at failing to lose weight despite following the equation is due in part to inaccurate nutrition information labels, and in part to variations in how much energy we actually absorb and how much energy we use<\/li>\n\n\n\n<li>The factors that affect absorption include how processed the food is; how the food has been prepared or cooked; and our unique gut bacteria<\/li>\n\n\n\n<li>The amount of energy we use is affected by four main factors of resting metabolic rate; thermic effect of eating; physical activity; and non-exercise activity thermogenesis<\/li>\n\n\n\n<li>Altering any one of the variables causes adjustments in other, seemingly unrelated variables.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>Gaining and losing fat changes the way your brain regulates your body weight. To understand this, let\u2019s have a refresher on how human metabolism actually works and explore what that means for your clients, most of whom are probably counting calories.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Energy balance<\/strong><\/h3>\n\n\n\n<p>You need a certain amount of energy (in the form of calories) to stay alive, as well as to move around. You can get this energy from food, or you can retrieve it from stored energy, such as your fat tissue. If you consume less energy than you expend, you will lose weight \u2013 and if you do the opposite, i.e. consume more energy than you expend, you will gain weight.<\/p>\n\n\n\n<p>In other words:&nbsp;<em>Changes in bodily tissues = Energy in \u2013 Energy out.<\/em><\/p>\n\n\n\n<p>This relationship between \u2018energy in\u2019 and \u2018energy out\u2019 is called the Energy Balance Equation, and it\u2019s the most commonly accepted model for calculating how much weight one will lose or gain over time.<\/p>\n\n\n\n<p>While the Energy Balance Equation determines body weight, it doesn\u2019t tell us much about body composition, which is influenced by things like sex hormone levels; macronutrient intake (especially protein); exercise style, frequency and intensity; age; medication use; genetic predisposition, and more.<\/p>\n\n\n\n<p>Understandably, people get very frustrated and confused with the Energy Balance Equation when the numbers don\u2019t seem to add up, or their results don\u2019t match their expectations. And it\u2019s a fair frustration. Most of the time, the numbers don\u2019t add up.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Expectations versus reality<\/strong><\/h3>\n\n\n\n<p>This mismatch between expectations versus reality is not because the Energy Balance Equation is wrong, or a myth. Nobody\u2019s body defies the laws of physics, even though it seems like that sometimes. It\u2019s because the equation is more complicated than it sounds.<\/p>\n\n\n\n<p>Many factors affect the Energy Balance Equation. What you do to \u2018energy in\u2019 affects what happens to \u2018energy out\u2019 and vice versa. The opposing sides aren\u2019t mutually exclusive.<\/p>\n\n\n\n<p>\u2018Eat less, move more\u2019 is a good start \u2013 but that advice alone isn\u2019t enough, because it doesn\u2019t take all of the complex, intersecting factors and feedback loops into account.<\/p>\n\n\n\n<p>Let\u2019s take a look at some of these factors, starting with the \u2018energy in\u2019 part of the equation.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Energy in<\/strong><\/h3>\n\n\n\n<p>\u2018Energy in\u2019 is trickier than it first sounds, for two main reasons:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Reason 1: Inaccurate nutrition labelling<\/strong><\/h4>\n\n\n\n<p>It might sound hard to believe, but the number of calories in a meal probably doesn\u2019t match the number of calories\/kilojoules on the labels or menu. The way companies, and even the government, come up with energy (kilojoule\/calorie) and nutrient estimates is incredibly complex, rather imprecise, and centuries-old. As a result, the Nutrition Information label that\u2019s mandatory on the packet of every foodstuff in your local supermarket can be off by as much as 20-25%, making it hard to accurately gauge what your \u2018energy in\u2019 actually is.<\/p>\n\n\n\n<p><em>Nutrition Information labels can have a margin of error of up to 25%<\/em><\/p>\n\n\n\n<p>Even if those food labels were correct, there\u2019s another reason that \u2018energy in\u2019 is no picnic to calculate.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Reason 2: We don\u2019t absorb all the energy we consume<\/strong><\/h4>\n\n\n\n<p>The amount of energy a food contains in the form of calories is not necessarily the amount of energy we absorb, store, and\/or use.<\/p>\n\n\n\n<p>Remember that the food we eat has to be digested and processed by our unique bodies. The innumerable steps involved in digestion, processing, absorption, storage, and use \u2014 as well as our own individual physiological makeup \u2014 can all change the energy balance game.<\/p>\n\n\n\n<p><strong>How processed?<\/strong><br>We absorb less energy from minimally processed carbohydrates and fats because they\u2019re harder to digest, and we absorb more energy from highly processed carbohydrates and fats, because they\u2019re easier to digest. The more processed a food is, the more digestion work is already done for you.<\/p>\n\n\n\n<p>Research has shown, for example, that we absorb more fat from peanut butter than from the same volume of whole peanuts. The researchers found that almost 38% of the fat in peanuts was excreted in the stool, rather than absorbed by the body, whereas seemingly all of the fat in the peanut butter was absorbed.<\/p>\n\n\n\n<p><strong>How prepped?&nbsp;<\/strong><br>We often absorb more energy from foods that are cooked (and\/or chopped, soaked, blended) because those processes break down plant and animal cells, increasing their bioavailability.<\/p>\n\n\n\n<p>When eating raw starchy foods (like sweet potatoes), we absorb very few of the calories. After cooking, however, the starches are much more available to us, tripling the number of calories absorbed. Interestingly, allowing starchy foods to then cool before eating them decreases the amount of calories we can extract from them again \u2013 mostly due to the formation of resistant starches.<\/p>\n\n\n\n<p><em>The way in which a food is prepared and whether it is cooked can affect its bioavailability<\/em><\/p>\n\n\n\n<p><strong>Gut bacteria<\/strong><br>We may absorb more or less energy depending on the types of bacteria in our gut. Some people have larger populations of a Bacteroidetes (a species of bacteria), which are better at extracting calories from tough plant cell walls than other bacteria species.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Margins of error<\/strong><\/h4>\n\n\n\n<p>By eating a diet rich in whole, minimally processed foods, the number of calories you absorb can be significantly less than you may expect. Plus, they require more calories to digest.<\/p>\n\n\n\n<p>Conversely, you will absorb more calories by eating lots of highly processed foods, and burn fewer calories in the digestive process. In addition, highly processed foods are less filling, more energy dense, and more likely to cause overeating.<\/p>\n\n\n\n<p>Since the number of calories someone thinks they\u2019re consuming could be off by 25% or more, their carefully curated daily intake of 1,600 calories could really be 1,200\u2026 or 2,000.<\/p>\n\n\n\n<p>Taking all of these factors into consideration, it becomes clear that this part of the equation should more accurately be:&nbsp;<em>Energy In = Actual calories eaten \u2013 Calories not absorbed<\/em><\/p>\n\n\n\n<p>Clearly, there\u2019s a big margin of error with regards energy input, even if you\u2019re a conscientious calorie counter. This doesn\u2019t invalidate the Energy Balance Equation. It just means that if you want an accurate calculation, you probably have to live in a fancy metabolic lab. For most people, it\u2019s not worth the effort.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Energy out<\/strong><\/h3>\n\n\n\n<p>\u2018Energy out\u2019 varies a lot from person to person: it\u2019s a dynamic, always-changing variable.<\/p>\n\n\n\n<p>There are four key parts to this complex system:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>1. Resting metabolic rate (RMR)<\/strong><\/h4>\n\n\n\n<p>RMR is the number of calories you burn each day at rest, just to breathe, think, and live. This represents roughly 60% of your \u2018energy out\u2019 and depends on weight, body composition, sex, age, genetic predisposition, and possibly (again) the bacterial population of your gut.<\/p>\n\n\n\n<p>A bigger body, in general, has a higher RMR, but, crucially, RMR varies up to 15% between individuals. So, a 90kg guy with an RMR of 1905 calories might find himself running alongside an identically-sized guy on the next treadmill who burns 286 more, or fewer, calories each day with no more, or less, effort.<\/p>\n\n\n\n<p><strong>2. Thermic effect of eating (TEE)<\/strong><\/p>\n\n\n\n<p>Digestion is an active metabolic process. Thermic effect of eating (TEE) is the number of calories you burn by eating, digesting and processing your food. This represents roughly 5-10% of your \u2018energy out\u2019.<\/p>\n\n\n\n<p>In general, you\u2019ll burn more calories in your effort to digest and absorb protein (20-30% of its calories) and carbs (5-6%) than you do fats (3%).<\/p>\n\n\n\n<p>And, as noted before, you\u2019ll burn more calories digesting minimally processed whole foods than you will highly processed foods.<\/p>\n\n\n\n<p><em>The less processed a food is, the greater the amount of energy you will burn digesting it<\/em><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>3. Physical activity (PA)<\/strong><\/h4>\n\n\n\n<p>You\u2019re a fitness professional, so you know this, but we\u2019ll recap anyway. Physical activity is the calories you burn from purposeful movement, such as walking, running, working out at the gym, gardening and riding a bike. Obviously, how much energy you expend through physical activity will change depending on how much you intentionally move around.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>4. Non-exercise activity thermogenesis (NEAT)<\/strong><\/h4>\n\n\n\n<p>Non-exercise activity thermogenesis (NEAT) is the calories you burn through fidgeting, staying upright, and all other physical activities except purposeful exercise. This, too, varies from person to person and day to day.<\/p>\n\n\n\n<p>Considering all of these factors, this part of the equation should more accurately be:<em>&nbsp;Energy out = RMR + TEE + PA + NEAT<\/em><\/p>\n\n\n\n<p>Each of these is highly variable. Which means the \u2018energy out\u2019 side of the equation may be just as hard to pin down as the \u2018energy in\u2019 side.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Revising the equation\u2026<\/strong><\/h3>\n\n\n\n<p>So, while the Energy Balance Equation sounds simple in principle, all these variables make it hard to know or control exactly how much energy you\u2019re taking in, absorbing, burning, and storing.<\/p>\n\n\n\n<p>So, revisiting that \u2018simple\u2019 Energy Balance Equation, we can see that, actually:<br><em>Changes in bodily tissues = [actual calories eaten \u2013 calories not absorbed] \u2013 [RMR + TEE + PA + NEAT]<\/em><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Knock-on effects of variables<\/strong><\/h4>\n\n\n\n<p>Even if all the variables in the final equation above were static, the Energy Balance Equation would be complicated enough. But things get crazy when you consider that altering any one of the variables causes adjustments in other, seemingly unrelated variables.<\/p>\n\n\n\n<p>This is a good thing, of course. Our human metabolisms evolved to keep us alive and functioning when food was scarce. One consequence is that when \u2018energy in\u2019 goes down, \u2018energy out\u2019 goes down to match it, because we burn fewer calories in response to eating less.<\/p>\n\n\n\n<p>Likewise, when \u2018energy in\u2019 goes up, \u2018energy out\u2019 tends to go up too, because we burn more calories in response to eating more.<\/p>\n\n\n\n<p>This isn\u2019t the case for everybody, and it doesn\u2019t work \u2018perfectly\u2019, but generally, that\u2019s how it goes and how our bodies avoid unwanted weight loss and starvation. It\u2019s how humans have survived for two million years. The body fights to maintain homeostasis.<\/p>\n\n\n\n<p>To illustrate this point, here\u2019s how your body tries to keep your weight steady when you take in less energy and start to lose weight:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Thermic effect of eating goes down because you\u2019re eating less.<\/li>\n\n\n\n<li>Resting metabolic rate goes down because you weigh less.<\/li>\n\n\n\n<li>Calories burned through physical activity go down since you weigh less.<\/li>\n\n\n\n<li>Non-exercise activity thermogenesis goes down as you eat less.<\/li>\n\n\n\n<li>Calories not absorbed goes down and you absorb more of what you eat.<\/li>\n<\/ul>\n\n\n\n<p>It\u2019s important to note that if you have lots of body fat to lose, many of these adaptations don\u2019t happen right away or are very modest initially. As you become leaner, however, this adaptive thermogenesis really ramps up.<\/p>\n\n\n\n<p><strong>Calorie cutting counterproductive?<\/strong><\/p>\n\n\n\n<p>In addition to these tangible effects on the equation, reducing actual calories eaten also causes hunger signals to increase, causing us to crave (and maybe eat) more. The net effect leads to a much lower rate of weight loss than might be expected \u2013 and in some cases, could even lead to weight re-gain.<\/p>\n\n\n\n<p><em>Reducing calorie consumption can lead to a much lower rate of weight loss than might be expected, and can even lead to weight re-gain<\/em><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Setting better expectations<\/strong><\/h3>\n\n\n\n<p>The calorie-cutting effect is just one example of the amazing and robust response to trying to manipulate one variable. There are similar responses when trying to manipulate each of the other variables in the equation. The point is, metabolism is much more complicated, and interdependent, than most people realise.<\/p>\n\n\n\n<p>Therefore, trying \u2018what used to work\u2019 for you, or relying on calorie counting, often won\u2019t get you the results you want. As your energy balance evolves, so must your strategies for losing fat or maintaining your weight.<\/p>\n\n\n\n<p>Understanding energy balance means setting better expectations about body change. Losing weight, and keeping it off, is accompanied by adaptive metabolic, neuroendocrine, autonomic, and other changes.<\/p>\n\n\n\n<p>It\u2019s also important to remember that how your metabolism reacts to changes in energy balance will be unique to you. How much you can lose or gain will depend on your age, your genetic makeup, your biological sex, if you\u2019ve had relatively more or less body fat and for how long, what medications you\u2019re taking, the makeup of your microbiome\u2026 and probably a whole lot of factors we don\u2019t even know about yet.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong><em>Brian St. Pierre, MS, RD, CSCS<\/em><\/strong><br><em>Brian is a US-based registered dietitian (RN), certified sports nutritionist (CISSN) and certified strength and conditioning specialist (CSCS). He spent three years as the Head Sports Nutritionist and as a Strength and Conditioning Coach at&nbsp;<\/em><em><a href=\"https:\/\/web.archive.org\/web\/20200419045505\/http:\/\/www.cresseyperformance.com\/\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Cressey Sports Performance<\/em><\/a><\/em><em>&nbsp;and is a nutrition coach with Precision Nutrition.&nbsp;<\/em><em><a href=\"https:\/\/web.archive.org\/web\/20200419045505\/https:\/\/www.precisionnutrition.com\/coach-profile-brian-st-pierre\" target=\"_blank\" rel=\"noreferrer noopener\">precisionnutrition.com<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Energy in minus energy out\u2019 is not as simple as it may seem, with a host of factors affecting both parts of the equation, writes dietitian and sports nutritionist&nbsp;Brian St. Pierre. THE QUICK READ Gaining and losing fat changes the way your brain regulates your body weight. To understand this, let\u2019s have a refresher on [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13,12],"tags":[],"class_list":["post-6706","post","type-post","status-publish","format-standard","hentry","category-training","category-personal-training"],"_links":{"self":[{"href":"https:\/\/www.fitnessnetwork.com.au\/wp-json\/wp\/v2\/posts\/6706","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fitnessnetwork.com.au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fitnessnetwork.com.au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fitnessnetwork.com.au\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fitnessnetwork.com.au\/wp-json\/wp\/v2\/comments?post=6706"}],"version-history":[{"count":0,"href":"https:\/\/www.fitnessnetwork.com.au\/wp-json\/wp\/v2\/posts\/6706\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.fitnessnetwork.com.au\/wp-json\/wp\/v2\/media?parent=6706"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fitnessnetwork.com.au\/wp-json\/wp\/v2\/categories?post=6706"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fitnessnetwork.com.au\/wp-json\/wp\/v2\/tags?post=6706"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}